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Structure of 75073-11-9
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5-Iodo-6-methylpyridin-2-amine delivers a reactive iodine handle and a basic pyridine nitrogen, enabling efficient cross-coupling and metal coordination. The methyl group enhances electron density at the ring, improving reactivity in palladium-catalyzed transformations. This bench-stable scaffold integrates readily into complex molecular architectures.
5-Iodo-6-methylpyridin-2-amine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its iodide functionality. The pyridin-2-amine core provides a robust scaffold for further derivatization, while the methyl group enhances metabolic stability and modulates electronic properties. This compound exhibits excellent bench stability and facilitates efficient synthesis of heterocyclic frameworks commonly found in kinase inhibitors and other bioactive molecules.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: