Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

6-Bromonaphthalen-2-amine

  • CAS No. 7499-66-3

  • Cat. No. CS-W001636
  • Purity≥96%
  • MDL No.MFCD01026466

*For research and further manufacturing use only, not for direct human use.

6-Bromonaphthalen-2-amine|CS-W001636

Structure of 7499-66-3

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 7499-66-3
  • Cat. No. CS-W001636
  • Purity ≥96%
  • MDL No. MFCD01026466
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₈BrN
  • Molecular Weight 222.08
  • Synonym(s) 6-Bromnaphthalen-2-amin
  • SMILES Nc1ccc2c(c1)ccc(c2)Br

Description

6-Bromonaphthalen-2-amine features a bromine atom at the 6-position and an amino group at the 2-position of the naphthalene core, enabling selective functionalization in cross-coupling reactions. This electron-rich scaffold integrates readily into complex architectures, offering enhanced solubility and stability under standard conditions.

Application

6-Bromonaphthalen-2-amine serves as a versatile building block in synthetic organic chemistry, enabling palladium-catalyzed cross-coupling reactions such as Suzuki-Miyaura and Buchwald-Hartwig couplings. Its bromine substituent provides high reactivity for C–C and C–N bond formation, while the aniline functionality offers compatibility with diverse functional groups. The compound exhibits excellent bench stability and is readily purified by recrystallization, making it ideal for constructing complex heterocyclic scaffolds and pharmaceutical intermediates.

Synthesis

  • Route1

    References

    • ABBOTT LABORATORIES; ROCKWAY, Todd W.; BETEBENNER, David A.; DEGOEY, David A.; FLENTGE, Charles A.; HUTCHINSON, Douglas K.; KATI, Warren M.; KRUEGER, Allan C.; LIU, Dachun; LONGENECKER, Kenton L.; PRATT, John K.; STEWART, Kent D.; WAGNER, Rolf Patent: WO2010/111437 A1, 2010 ; Location in patent: Page/Page column 74 ; WO 2010/111437 A1
  • Route2

    References

    • THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA Patent: WO2008/124812 A1, 2008 ; Location in patent: Page/Page column 53 ;
  • Route3

    References

    • InterMune, Inc. Patent: US2011/152246 A1, 2011 ; Location in patent: Page/Page column 264 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   26.02
  • LogP   3.1845
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 6-Bromonaphthalen-2-amine sigma6-Bromonaphthalen-2-amine manufacturer6-Bromonaphthalen-2-amine price6-Bromonaphthalen-2-amine structure6-Bromonaphthalen-2-amine SDSbuy 6-Bromonaphthalen-2-amine6-Bromonaphthalen-2-amine supplier6-Bromonaphthalen-2-amine uses6-Bromonaphthalen-2-amine molecular weightprice of 6-Bromonaphthalen-2-amine6-Bromonaphthalen-2-amine chemical name formula of 6-Bromonaphthalen-2-amine
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label