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CS-W001157 4
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6-Bromonaphthalen-1-amine

  • CAS No. 591253-73-5

  • Cat. No. CS-0121654
  • Purity≥98%
  • MDL No.MFCD17012559

*For research and further manufacturing use only, not for direct human use.

6-Bromonaphthalen-1-amine|CS-0121654

Structure of 591253-73-5

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General Information

  • CAS No. 591253-73-5
  • Cat. No. CS-0121654
  • Purity ≥98%
  • MDL No. MFCD17012559
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₈BrN
  • Molecular Weight 222.08
  • Synonym(s) 6-bromo-1-naphthalenamine
  • SMILES NC1=C2C=CC(Br)=CC2=CC=C1

Description

6-Bromonaphthalen-1-amine features a bromine substituent at the 6-position of naphthalene and a primary amine group at the 1-position, enabling direct coupling in Pd-catalyzed cross-coupling reactions. The electron-rich aromatic core supports efficient functionalization, while the bench-stable nature facilitates handling under standard conditions.

Application

6-Bromonaphthalen-1-amine serves as a versatile building block in synthetic organic chemistry, enabling palladium-catalyzed cross-coupling reactions due to its stable bromo group and amine functionality. The molecule exhibits good bench stability and facilitates the construction of biaryl scaffolds, heterocycles, and functionalized naphthalene derivatives under standard reaction conditions. Its compatibility with diverse coupling partners and ease of purification make it a practical choice for medicinal chemistry and materials synthesis workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   3.1845
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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