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CS-W001157 4
Total: USD 88.00

7-Bromonaphthalen-2-amine

  • CAS No. 590417-30-4

  • Cat. No. CS-0108579
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

7-Bromonaphthalen-2-amine|CS-0108579

Structure of 590417-30-4

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General Information

  • CAS No. 590417-30-4
  • Cat. No. CS-0108579
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₈BrN
  • Molecular Weight 222.08
  • Synonym(s) 2-Amino-7-bromonaphthalene
  • SMILES NC1=CC=C2C=CC(Br)=CC2=C1

Description

7-Bromonaphthalen-2-amine features a bromine substituent at the 7-position of naphthalene, flanked by an amine group at the 2-position. This electron-deficient scaffold enables direct coupling in cross-coupling reactions and serves as a key intermediate for functionalized polycyclic architectures in pharmaceutical and materials synthesis.

Application

7-Bromonaphthalen-2-amine serves as a versatile building block in synthetic organic chemistry, enabling palladium-catalyzed cross-coupling reactions such as Suzuki-Miyaura and Buchwald-Hartwig arylations. The bromine and amino groups exhibit complementary reactivity, facilitating sequential functionalization and the construction of complex heterocyclic scaffolds. Its bench-stable nature and compatibility with standard purification protocols make it well-suited for medicinal chemistry and materials science applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   3.1845
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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