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CS-W001157 4
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Methyl 4-formyl-3-methoxybenzoate

  • CAS No. 74733-24-7

  • Cat. No. CS-0038404
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Methyl 4-formyl-3-methoxybenzoate|CS-0038404

Structure of 74733-24-7

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General Information

  • CAS No. 74733-24-7
  • Cat. No. CS-0038404
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₀O₄
  • Molecular Weight 194.18
  • Synonym(s) Benzoic acid, 4-formyl-3-methoxy-, methyl ester
  • SMILES COC1=CC(=CC=C1C=O)C(=O)OC

Description

Methyl 4-formyl-3-methoxybenzoate features a strategically positioned aldehyde group flanked by electron-donating methoxy and ester functionalities, enabling direct incorporation into diverse synthetic scaffolds. This bench-stable, moisture-tolerant reagent facilitates efficient access to functionalized aromatic systems through coupling, condensation, or cyclization reactions under standard conditions.

Application

Methyl 4-formyl-3-methoxybenzoate serves as a versatile building block in synthetic organic chemistry, enabling efficient access to functionalized aromatic scaffolds. The aldehyde group facilitates nucleophilic additions and reductive aminations, while the methoxy and ester functionalities offer orthogonal handles for selective transformations. Its bench-stable nature and compatibility with common coupling and protection strategies make it well-suited for medicinal chemistry campaigns and process development workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   52.6
  • LogP   1.2943
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   3

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