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CS-W001157 4
Total: USD 88.00

2-Methoxyterephthalic acid

  • CAS No. 5156-00-3

  • Cat. No. CS-0061926
  • Purity≥95%
  • MDL No.MFCD20638219

*For research and further manufacturing use only, not for direct human use.

2-Methoxyterephthalic acid|CS-0061926

Structure of 5156-00-3

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General Information

  • CAS No. 5156-00-3
  • Cat. No. CS-0061926
  • Purity ≥95%
  • MDL No. MFCD20638219
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₈O₅
  • Molecular Weight 196.16
  • Synonym(s) None
  • SMILES O=C(O)C1=CC=C(C(=O)O)C(OC)=C1

Description

2-Methoxyterephthalic acid features a rigid aromatic core with two carboxylic acid groups flanked by a methoxy substituent, enabling precise coordination in metal-organic frameworks. This electron-donating group enhances solubility and modulates reactivity under standard conditions, facilitating use in modular synthesis of functionalized materials.

Application

2-Methoxyterephthalic acid serves as a versatile building block in the synthesis of functionalized aromatic polymers and bioactive heterocycles. Its ortho-dicarboxylic acid functionality enables efficient coordination in metal-organic frameworks and facilitates esterification or amidation for downstream conjugation. The methoxy group enhances solubility and provides a handle for further derivatization, while the compound exhibits excellent bench stability and ease of purification in standard organic workflows.

Synthesis

  • Route1

    References

    • Hannah, David T.B.; Sherrington, David C. Journal of Materials Chemistry, 1997 , vol. 7, # 10 p. 1985 - 1991
  • Route2

    References

    • Hidefumi Hirai Patent: US5319134 A1, 1994 ;
  • Route3

    References

    • Schall Chemische Berichte, 1879 , vol. 12, p. 818,821

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   83.83
  • LogP   1.0916
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   3

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