Boc-D-Homoserine

Name: Boc-D-Homoserine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 745011-75-0
Cat. No. CS-W018574
Purity≥98%
MDL No.MFCD12545888

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

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Structure of 745011-75-0

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General Information

CAS No. 745011-75-0
Cat. No. CS-W018574
Purity ≥98%
MDL No. MFCD12545888
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₉H₁₇NO₅
Molecular Weight 219.24
Synonym(s) None
SMILES OCC[C@H](C(O)=O)NC(OC(C)(C)C)=O

Description

Boc-D-Homoserine features a protected D-homoserine backbone, enabling stable incorporation into peptide sequences and synthetic intermediates. The tert-butoxycarbonyl group ensures orthogonal handling during multi-step syntheses, while the chiral center supports stereoselective transformations in bioactive molecule construction.

Application

Boc-D-Homoserine serves as a key chiral building block in peptide synthesis and medicinal chemistry, offering stable protection of the amine group under acidic conditions. Its hydroxyl functionality enables selective derivatization for heterocycle formation or conjugation strategies. The Boc group facilitates straightforward deprotection with trifluoroacetic acid, enabling efficient access to D-homoserine derivatives. This compound exhibits excellent bench stability and compatibility with standard coupling protocols, making it a practical choice for scalable synthesis and fragment assembly.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

TPSA 95.86
LogP 0.3467
H_Acceptors 4
H_Donors 3
Rotatable_Bonds 4

Other Classifications

Bioactive Molecules Peptides

Life Science Amino Acids and their Derivatives Serine and derivatives

Life Science Amino Acids and their Derivatives N-protected amino acid

Chemical Biology Pharmaceutical Development and Drug Discovery Research Peptide Chemistry Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Peptide Chemistry Unnatural Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Peptide Chemistry Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Peptide Chemistry Unnatural Amino Acid Derivatives

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Unnatural Amino Acid Derivatives

Biochemistry Biochemicals and Reagents Amino Acids N-Protected Amino Acids

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Boc-D-Homoserine

CAS No. 745011-75-0

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