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CS-W001157 4
Total: USD 88.00

7-Fluoronaphthalene-1,3-diol

  • CAS No. 2460027-79-4

  • Cat. No. CS-0159077
  • Purity≥98%
  • MDL No.MFCD33022268

*For research and further manufacturing use only, not for direct human use.

7-Fluoronaphthalene-1,3-diol|CS-0159077

Structure of 2460027-79-4

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General Information

  • CAS No. 2460027-79-4
  • Cat. No. CS-0159077
  • Purity ≥98%
  • MDL No. MFCD33022268
  • Storage RT, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₇FO₂
  • Molecular Weight 178.16
  • Synonym(s) None
  • SMILES OC1=CC(O)=CC2=CC=C(F)C=C21

Description

7-Fluoronaphthalene-1,3-diol features a fluorinated naphthalene core with hydroxyl groups at positions 1 and 3, enabling strong hydrogen-bonding capacity and enhanced solubility. This arrangement imparts high chemical stability and facilitates integration into bioactive scaffolds for medicinal chemistry applications.

Application

7-Fluoronaphthalene-1,3-diol serves as a versatile building block for functionalized naphthalene scaffolds, enabling direct substitution at C1 and C3 via nucleophilic aromatic substitution or transition-metal-catalyzed coupling. Its fluorine substituent enhances metabolic stability and modulates electronic properties, while the diol functionality offers orthogonal handles for protection or derivatization. Bench-stable and compatible with standard synthetic workflows, it facilitates rapid access to complex polycyclic architectures relevant in medicinal chemistry and materials science.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H302-H318
Precautionary Statements : P264-P270-P280-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   40.46
  • LogP   2.3901
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   0

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