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CS-W001157 4
Total: USD 88.00

Boc-D-Ser(tBu)-OH

  • CAS No. 248921-66-6

  • Cat. No. CS-W019152
  • Purity≥95%
  • MDL No.MFCD09751020

*For research and further manufacturing use only, not for direct human use.

Boc-D-Ser(tBu)-OH|CS-W019152

Structure of 248921-66-6

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General Information

  • CAS No. 248921-66-6
  • Cat. No. CS-W019152
  • Purity ≥95%
  • MDL No. MFCD09751020
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₂₃NO₅
  • Molecular Weight 261.32
  • Synonym(s) None
  • SMILES O=C(O)[C@H](NC(OC(C)(C)C)=O)COC(C)(C)C

Description

Boc-D-Ser(tBu)-OH is a bench-stable, moisture-tolerant amino acid derivative featuring a protected D-serine side chain. This building block integrates seamlessly into peptide synthesis workflows, enabling efficient access to D-amino acid-containing sequences with enhanced metabolic stability and resistance to proteolytic degradation.

Application

Boc-D-Ser(tBu)-OH serves as a stable, bench-ready building block for the synthesis of D-serine-containing peptides and peptidomimetics. The Boc group provides orthogonal protection for the amine, while the tert-butyl ether ensures high stability and compatibility with standard peptide coupling protocols. Its defined stereochemistry and predictable reactivity facilitate efficient incorporation into complex scaffolds, enabling reliable access to bioactive sequences in medicinal chemistry and process development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   84.86
  • LogP   1.7794
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   4

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