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Structure of 73418-88-9
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Methyl 5-aminopyrimidine-2-carboxylate features a pyrimidine core bearing both amino and ester functionalities, enabling direct incorporation into heterocyclic scaffolds. The para-amino group enhances electron density for downstream coupling, while the methyl ester facilitates selective hydrolysis or derivatization under standard conditions. This bench-stable compound serves as a key intermediate in the synthesis of bioactive nucleoside analogs and kinase inhibitors.
Methyl 5-aminopyrimidine-2-carboxylate serves as a versatile building block in medicinal chemistry, enabling efficient access to pyrimidine-based scaffolds. The amino and ester functionalities offer orthogonal reactivity for downstream modifications, including amide coupling, nucleophilic substitution, and metal-catalyzed cross-coupling reactions. Its bench-stable nature and compatibility with standard purification methods make it well-suited for multi-step synthesis workflows in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: