Cyclopropanemethylamine hydrochloride

Name: Cyclopropanemethylamine hydrochloride
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

SDS

CAS No. 7252-53-1
Cat. No. CS-0132848
Purity≥97%
MDL No.MFCD00012544

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Cyclopropanemethylamine hydrochloride|CS-0132848

Structure of 7252-53-1

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General Information

CAS No. 7252-53-1
Cat. No. CS-0132848
Purity ≥97%
MDL No. MFCD00012544
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₄H₁₀ClN
Molecular Weight 107.58
Synonym(s) cyclopropylmethanamine,hydrochloride; Cyclopropanemethylamine hydrochloride
SMILES NCC1CC1.Cl

Description

Cyclopropanemethylamine hydrochloride offers a strained cyclopropyl ring fused to a primary amine, delivering high reactivity in synthetic transformations. This bench-stable salt facilitates efficient incorporation into bioactive molecules and serves as a key scaffold in medicinal chemistry.

Application

Cyclopropanemethylamine hydrochloride serves as a versatile building block in medicinal chemistry, enabling the incorporation of a rigid cyclopropylmethyl moiety into bioactive molecules. Its stable hydrochloride salt form facilitates handling and storage, while the primary amine functionality supports facile derivatization via alkylation, acylation, and coupling reactions. Widely used in the synthesis of heterocyclic scaffolds and peptide mimetics, it functions as a key intermediate in the development of targeted therapeutics.

Synthesis

Route1
- 5500-21-0
- ~%
- In-stock
  
  7252-53-1
References
- Synthesis, , # 8 p. 605 - 606

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

Quality Control

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SDS
COA

Computational Chemistry Data

TPSA 26.02
LogP 0.7769
H_Acceptors 1
H_Donors 1
Rotatable_Bonds 1

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Other Classifications

Building Blocks Skeleton Fatty ring compounds Cyclopropane compounds

Key Words

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