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CS-W001157 4
Total: USD 88.00

(S)-Tetrahydrofurfurylamine

  • CAS No. 7175-81-7

  • Cat. No. CS-W011316
  • Purity≥95%
  • MDL No.MFCD00085303

*For research and further manufacturing use only, not for direct human use.

(S)-Tetrahydrofurfurylamine|CS-W011316

Structure of 7175-81-7

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General Information

  • CAS No. 7175-81-7
  • Cat. No. CS-W011316
  • Purity ≥95%
  • MDL No. MFCD00085303
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₁NO
  • Molecular Weight 101.15
  • Synonym(s) None
  • SMILES NC[C@@H]1CCCO1

Description

(S)-Tetrahydrofurfurylamine is a chiral, bench-stable amine featuring a saturated furan ring framework. This configuration imparts distinct stereochemical control in asymmetric synthesis, enabling selective functionalization in pharmaceutical intermediates and fine chemical applications. The hydroxyl-bearing heterocycle enhances solubility and reactivity in polar media.

Application

(S)-Tetrahydrofurfurylamine serves as a valuable chiral building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and functionalized amine derivatives. Its tetrahydrofuran ring imparts enhanced stability and solubility, while the primary amine functionality facilitates straightforward derivatization via acylation, alkylation, and reductive amination. The stereogenic center supports enantioselective synthesis, making it particularly useful in the construction of chiral scaffolds for pharmaceutical development.

Safety Information

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GHS Pictogram :
GHS No : GHS02,GHS07
Signal Word : Warning
UN#: 2943
Class : 3
Packing Group : Ⅲ
Hazard Statements : H226-H315-H319-H335
Precautionary Statements : P210-P233-P240-P241-P242-P243-P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P370+P378-P405-P501

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Computational Chemistry Data

  • TPSA   35.25
  • LogP   0.1241
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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