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CS-W001157 4
Total: USD 88.00

6-(Methoxycarbonyl)picolinic acid

  • CAS No. 7170-36-7

  • Cat. No. CS-W019323
  • Purity≥97%
  • MDL No.MFCD00806109

*For research and further manufacturing use only, not for direct human use.

6-(Methoxycarbonyl)picolinic acid|CS-W019323

Structure of 7170-36-7

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General Information

  • CAS No. 7170-36-7
  • Cat. No. CS-W019323
  • Purity ≥97%
  • MDL No. MFCD00806109
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₇NO₄
  • Molecular Weight 181.15
  • Synonym(s) Pyridine-2,6-dicarboxylic acid monomethyl ester
  • SMILES COC(=O)C1=NC(=CC=C1)C(=O)O

Description

Methyl 2,3-O-isopropylidene-beta-D-ribofuranoside is used for the manufacture of fine chemicals, and Industrial use resulting in manufacture of intermediates.

Application

6-(Methoxycarbonyl)picolinic acid serves as a versatile building block in medicinal chemistry, enabling efficient synthesis of pyridine-based scaffolds. Its ortho-carboxylate functionality facilitates direct amidation, esterification, and cyclization reactions, while the methoxycarbonyl group offers enhanced stability and ease of purification. This compound functions effectively in coupling protocols and heterocycle formation, supporting scalable workflows in API development.

Synthesis

  • Route1

    References

    • Ager; Prakash Synthetic Communications, 1995 , vol. 25, # 5 p. 739 - 742
  • Route2
    • null|null
      67-56-1
    • In-stock
      Pyridine-2,6-dicarboxylic acid|CS-0016012
      499-83-2
    • ~50%
    • In-stock
      6-(Methoxycarbonyl)picolinic acid|CS-W019323
      7170-36-7

    References

    • Ryan, Patrick E.; Canard, Gabriel; Koeller, Sylvain; Bocquet, Bernard; Piguet, Claude Inorganic Chemistry, 2012 , vol. 51, # 18 p. 10012 - 10024
  • Route3

    References

    • Tetrahedron, , vol. 67, # 44 p. 8458 - 8464

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   76.49
  • LogP   0.5664
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   2

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