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CS-W001157 4
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1-Methylcyclopropaneacetic acid

  • CAS No. 71199-15-0

  • Cat. No. CS-0029552
  • Purity≥95%
  • MDL No.MFCD18632734

*For research and further manufacturing use only, not for direct human use.

1-Methylcyclopropaneacetic acid|CS-0029552

Structure of 71199-15-0

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General Information

  • CAS No. 71199-15-0
  • Cat. No. CS-0029552
  • Purity ≥95%
  • MDL No. MFCD18632734
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₀O₂
  • Molecular Weight 114.14
  • Synonym(s) 2-(1-Methylcyclopropyl)acetic acid; Cyclopropanamine,1-methyl
  • SMILES O=C(O)CC1(C)CC1

Description

1-Methylcyclopropaneacetic acid features a strained cyclopropyl ring fused to a carboxylic acid group, delivering high reactivity for conjugate addition and cycloaddition processes. This sterically constrained scaffold enables precise control in synthetic transformations, particularly in the construction of chiral building blocks and bioactive molecule frameworks under standard conditions.

Application

1-Methylcyclopropaneacetic acid serves as a valuable chiral building block in medicinal chemistry, enabling the synthesis of bioactive molecules through its strained cyclopropyl motif. Its functional group tolerance and bench stability facilitate straightforward derivatization, while the methyl-substituted cyclopropane core provides defined stereochemical control in asymmetric synthesis and scaffold diversification.

Synthesis

  • Route1
    • 2-(1-Methylcyclopropyl)acetonitrile|CS-0343573
      1057002-82-0
    • ~%
    • In-stock
      1-Methylcyclopropaneacetic acid|CS-0029552
      71199-15-0

    References

    • Kon-I, Kana; Matsumizu, Miyako; Shima, Akiko Patent: US2006/94750 A1, 2006 ; Location in patent: Page/Page column 30 ; US 20060094750 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3265
Class : 8
Packing Group : Ⅲ
Hazard Statements : H302-H315-H318-H335
Precautionary Statements : P261-P280-P302+P352

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   1.2612
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   2

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