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Structure of 69875-49-6
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4-Chloroquinoline-3-carbonitrile features a chlorine atom at the 4-position and a nitrile group at the 3-position of the quinoline core, delivering enhanced electron-withdrawing character and improved solubility in organic solvents. This scaffold integrates readily into pharmaceutical intermediates and functional materials due to its stability under standard conditions and compatibility with diverse coupling reactions.
4-Chloroquinoline-3-carbonitrile serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its orthogonal reactivity profile. The chlorine and nitrile groups provide distinct handles for further functionalization, while the quinoline core offers inherent stability and favorable pharmacophoric properties. Its bench-stable nature and compatibility with diverse reaction conditions make it well-suited for modular synthesis of heterocyclic scaffolds and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: