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CS-W001157 4
Total: USD 88.00

3-(Chloromethyl)pyridine hydrochloride

  • CAS No. 6959-48-4

  • Cat. No. CS-W003964
  • Purity≥97%
  • MDL No.MFCD00012818
  • HazMat Fee +

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    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

3-(Chloromethyl)pyridine hydrochloride|CS-W003964

Structure of 6959-48-4

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Description

3-(Chloromethyl)pyridine hydrochloride features a pyridine ring bearing a chloromethyl group, enabling efficient alkylation reactions. The hydrochloride salt enhances solubility and stability under standard conditions, facilitating straightforward handling in synthetic workflows. This reagent serves as a direct conduit for introducing pyridylmethyl functionality into complex molecular architectures.

Application

3-(Chloromethyl)pyridine hydrochloride serves as a versatile building block for pyridine-based heterocycles, enabling efficient functionalization via nucleophilic substitution. The chloromethyl group exhibits high reactivity toward amines, thiols, and carbanions under mild conditions, facilitating rapid access to pharmacophores and ligand scaffolds. Its crystalline solid form ensures excellent bench stability and ease of handling, while the hydrochloride salt enhances solubility in polar solvents without compromising reactivity. Widely used in medicinal chemistry and catalysis research, it functions reliably in standard synthetic workflows requiring selective alkylation or chain extension.

General Information

  • CAS No. 6959-48-4
  • Cat. No. CS-W003964
  • Purity ≥97%
  • MDL No. MFCD00012818
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₇Cl₂N
  • Molecular Weight 164.03
  • Synonym(s) 3-Picolyl Chloride Hydrochloride
  • SMILES ClCC1=CN=CC=C1.Cl

Computational Chemistry Data

  • TPSA   12.89
  • LogP   2.2422
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07,GHS08
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group :
Hazard Statements : H302-H314-H341
Precautionary Statements : P260-P264-P270-P280-P301+P330+P331-P304+P340-P330-P363-P405-P501

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