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Structure of 6959-48-4
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3-(Chloromethyl)pyridine hydrochloride features a pyridine ring bearing a chloromethyl group, enabling efficient alkylation reactions. The hydrochloride salt enhances solubility and stability under standard conditions, facilitating straightforward handling in synthetic workflows. This reagent serves as a direct conduit for introducing pyridylmethyl functionality into complex molecular architectures.
3-(Chloromethyl)pyridine hydrochloride serves as a versatile building block for pyridine-based heterocycles, enabling efficient functionalization via nucleophilic substitution. The chloromethyl group exhibits high reactivity toward amines, thiols, and carbanions under mild conditions, facilitating rapid access to pharmacophores and ligand scaffolds. Its crystalline solid form ensures excellent bench stability and ease of handling, while the hydrochloride salt enhances solubility in polar solvents without compromising reactivity. Widely used in medicinal chemistry and catalysis research, it functions reliably in standard synthetic workflows requiring selective alkylation or chain extension.
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GHS Pictogram :
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GHS No : GHS05,GHS07,GHS08
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅱ
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Hazard Statements : H302-H314-H341
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Precautionary Statements : P260-P264-P270-P280-P301+P330+P331-P304+P340-P330-P363-P405-P501
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Lot numbers can be found on the outside label of a product: