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CS-W001157 4
Total: USD 88.00

1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)uracil

  • CAS No. 69123-94-0

  • Cat. No. CS-W018472
  • Purity≥97%
  • MDL No.MFCD00870798

*For research and further manufacturing use only, not for direct human use.

1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)uracil|CS-W018472

Structure of 69123-94-0

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General Information

  • CAS No. 69123-94-0
  • Cat. No. CS-W018472
  • Purity ≥97%
  • MDL No. MFCD00870798
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₁FN₂O₅
  • Molecular Weight 246.19
  • Synonym(s) None
  • SMILES O=C(NC(C=C1)=O)N1[C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2F

Description

This fluorinated uracil analog integrates a 2-deoxy-2-fluoro-beta-D-arabinofuranosyl moiety, conferring enhanced metabolic stability and resistance to enzymatic degradation. Designed for nucleoside analog applications, it serves as a potent inhibitor of viral replication pathways, particularly in antiviral drug development.

Application

1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)uracil serves as a stable nucleoside analog enabling site-specific fluorination in antiviral and anticancer prodrug development. Its 2′-fluoro substitution enhances metabolic stability while preserving base-pairing fidelity, facilitating incorporation into oligonucleotides and serving as a key building block for nucleoside therapeutics. The arabinose sugar conformation supports efficient glycosylation reactions and improves resistance to enzymatic degradation.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H320-H335
Precautionary Statements : P264-P270-P330

Quality Control

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Computational Chemistry Data

  • TPSA   104.55
  • LogP   -1.8747
  • H_Acceptors   6
  • H_Donors   3
  • Rotatable_Bonds   2

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