Lot numbers can be found on the outside label of a product:
2′,2′-Difluorodeoxyuridine
-
CAS No. 114248-23-6
- Cat. No. CS-0146489
- Purity≥98%
- MDL No.MFCD00871912
*For research and further manufacturing use only, not for direct human use.
Structure of 114248-23-6
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 114248-23-6
- Cat. No. CS-0146489
- Purity ≥98%
- MDL No. MFCD00871912
- Storage -20°C
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₉H₁₀F₂N₂O₅
- Molecular Weight 264.18
- Synonym(s) dFdU; 2',2'-Difluoro-2'-deoxyuridine
- SMILES O=C(N1)N([C@@H]2O[C@H](CO)[C@@H](O)C2(F)F)C=CC1=O
Description
Useful derivative for the synthesis of phosphoserine peptides by the Fmoc SPPS global phosphorylation methodology. Associated Protocols and Technical ArticlesCleavage and Deprotection Protocols for Fmoc SPPS
Application
2′,2′-Difluorodeoxyuridine serves as a key nucleoside building block for the synthesis of antiviral and anticancer agents. Its difluorinated sugar moiety enhances metabolic stability and facilitates incorporation into DNA, enabling targeted inhibition of viral polymerases and DNA replication enzymes. The compound exhibits robust bench stability and compatibility with standard phosphorylation and coupling protocols, making it a reliable intermediate in medicinal chemistry workflows involving nucleoside analogs.
Synthesis
-
Route1
-
143157-27-1 - ~94%
-
In-stock
114248-23-6
References
-
ALIOS BIOPHARMA, INC.; Beigelman, Leonid; Wang, Guangyi; Smith, David Bernard; Deval, Jerome; Prhavc, Marija Patent: US2013/165400 A1, 2013 ; Location in patent: Paragraph 0420; 0421 ;
-
-
Route2
-
1201895-94-4 - ~91%
-
In-stock
114248-23-6
References
-
Chou; Heath; Patterson; Poteet; Lakin; Hunt Synthesis, 1992 , # 6 p. 565 - 570
-
-
Route3
-
In-stock
122111-03-9 - ~%
-
In-stock
114248-23-6
References
-
US2013/165400 A1, ;
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 104.55
- LogP -1.5775
- H_Acceptors 6
- H_Donors 3
- Rotatable_Bonds 2
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- 2′,2′-Difluorodeoxyuridine sigma2′,2′-Difluorodeoxyuridine manufacturer2′,2′-Difluorodeoxyuridine price2′,2′-Difluorodeoxyuridine structure2′,2′-Difluorodeoxyuridine SDSbuy 2′,2′-Difluorodeoxyuridine2′,2′-Difluorodeoxyuridine supplier2′,2′-Difluorodeoxyuridine uses2′,2′-Difluorodeoxyuridine molecular weightprice of 2′,2′-Difluorodeoxyuridine2′,2′-Difluorodeoxyuridine chemical name formula of 2′,2′-Difluorodeoxyuridine