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CS-W001157 4
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Mal-amido-PEG8-C2-acid

  • CAS No. 1334177-86-4

  • Cat. No. CS-0020926
  • Purity≥97%
  • MDL No.MFCD13184956

*For research and further manufacturing use only, not for direct human use.

Mal-amido-PEG8-C2-acid|CS-0020926

Structure of 1334177-86-4

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General Information

  • CAS No. 1334177-86-4
  • Cat. No. CS-0020926
  • Purity ≥97%
  • MDL No. MFCD13184956
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₆H₄₄N₂O₁₃
  • Molecular Weight 592.63
  • Synonym(s) None
  • SMILES O=C(CCN1C(C=CC1=O)=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O

Description

Mal-amido-PEG8-C2-acid features a maleimide-functionalized PEG linker with a C2 carboxylic acid terminus, enabling site-specific conjugation to thiol-containing biomolecules. The extended PEG8 chain provides enhanced solubility and reduced aggregation, while the terminal acid facilitates further derivatization or immobilization. This bifunctional architecture supports efficient bioconjugation workflows in protein labeling, probe development, and surface tethering applications.

Application

Mal-amido-PEG8-C2-acid serves as a versatile bifunctional linker for conjugation and immobilization applications. The maleimide group enables selective, rapid thiol-addition under physiological conditions, while the terminal carboxylic acid facilitates amide coupling or further functionalization. The PEG8 spacer provides enhanced solubility and reduced non-specific binding, making it ideal for bioconjugation workflows requiring stability, flexibility, and efficient purification.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   177.62
  • LogP   -0.9748
  • H_Acceptors   12
  • H_Donors   2
  • Rotatable_Bonds   30

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