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Structure of 690261-64-4
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This pyrimidine derivative features a piperidinyl substituent at the 2-position, conferring enhanced solubility and metabolic stability. The hydrochloride salt form ensures excellent crystallinity and handling convenience. It serves as a key scaffold in medicinal chemistry for kinase inhibitors and other bioactive molecules.
2-(Piperidin-4-yl)pyrimidine hydrochloride serves as a versatile building block in medicinal chemistry, enabling the construction of pyrimidine-based scaffolds prevalent in kinase inhibitors and antiviral agents. The piperidinyl nitrogen provides a readily functionalizable site for derivatization, while the hydrochloride salt enhances solubility and stability for handling. It exhibits robust compatibility with standard coupling reactions and functions effectively in parallel synthesis campaigns requiring reliable heterocyclic intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: