Lot numbers can be found on the outside label of a product:
Methyl 2-bromo-6-chlorobenzoate
-
CAS No. 685892-23-3
- Cat. No. CS-0094451
- Purity≥98%
- MDL No.MFCD03789160
*For research and further manufacturing use only, not for direct human use.
Structure of 685892-23-3
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 685892-23-3
- Cat. No. CS-0094451
- Purity ≥98%
- MDL No. MFCD03789160
- Storage Store at room temperature
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₈H₆BrClO₂
- Molecular Weight 249.49
- Synonym(s) methyl2-bromo-6-chlorobenzoate
- SMILES O=C(OC)C1=C(Cl)C=CC=C1Br
Description
Methyl 2-bromo-6-chlorobenzoate is a halogenated aromatic ester featuring strategically positioned bromo and chloro substituents on the benzene ring. This combination enables selective cross-coupling reactions, particularly in palladium-catalyzed processes. The methyl ester group provides a handle for further functionalization, while the electron-withdrawing halogens enhance reactivity. Bench-stable and moisture-tolerant, it serves as a key intermediate in pharmaceutical and agrochemical synthesis.
Application
Methyl 2-bromo-6-chlorobenzoate serves as a versatile building block for the synthesis of substituted aromatic scaffolds. The ortho-bromine and meta-chlorine substituents enable sequential cross-coupling reactions, facilitating access to biaryl and heterocyclic architectures. Its stability under standard reaction conditions and compatibility with palladium-catalyzed transformations make it ideal for modular synthetic approaches in medicinal chemistry and materials science.
Synthesis
-
Route1
-
In-stock
93224-85-2 -
77-78-1 - ~99%
-
In-stock
685892-23-3
References
-
Biswas, Kaustav; Peterkin, Tanya A. N.; Bryan, Marian C.; Arik, Leyla; Lehto, Sonya G.; Sun, Hong; Hsieh, Feng-Yin; Xu, Cen; Fremeau, Robert T.; Allen, Jennifer R. Journal of Medicinal Chemistry, 2011 , vol. 54, # 20 p. 7232 - 7246
-
-
References
-
MERCK SHARP and DOHME CORP.; BARR, Kenneth, Jay; BEINSTOCK, Corey; MACLEAN, John; ZHANG, Hongjun; BERESIS, Richard, Thomas; ZHANG, Dongshan Patent: WO2014/28589 A2, 2014 ; Location in patent: Page/Page column 56 ;
-
-
Route3
-
In-stock
93224-85-2
-
18107-18-1
- ~%
-
In-stock
685892-23-3
References
-
US2003/220375 A1, ;
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 26.3
- LogP 2.8891
- H_Acceptors 2
- H_Donors 0
- Rotatable_Bonds 1
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- Methyl 2-bromo-6-chlorobenzoate sigmaMethyl 2-bromo-6-chlorobenzoate manufacturerMethyl 2-bromo-6-chlorobenzoate priceMethyl 2-bromo-6-chlorobenzoate structureMethyl 2-bromo-6-chlorobenzoate SDSbuy Methyl 2-bromo-6-chlorobenzoateMethyl 2-bromo-6-chlorobenzoate supplierMethyl 2-bromo-6-chlorobenzoate usesMethyl 2-bromo-6-chlorobenzoate molecular weightprice of Methyl 2-bromo-6-chlorobenzoateMethyl 2-bromo-6-chlorobenzoate chemical name formula of Methyl 2-bromo-6-chlorobenzoate