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Structure of 685513-97-7
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Methyl 4-chloro-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine-5-carboxylate features a sterically shielded triisopropylsilyl group that enhances stability and facilitates selective functionalization. The chloro substituent enables downstream cross-coupling reactions, while the pyrrolo[2,3-b]pyridine core provides a rigid, electron-deficient scaffold ideal for medicinal chemistry applications.
Methyl 4-chloro-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine-5-carboxylate serves as a versatile building block for the synthesis of functionalized pyrrolopyridine scaffolds. The triisopropylsilyl group provides robust protection and enhanced solubility, enabling facile deprotection and orthogonal handling in multi-step sequences. The 4-chloro substituent facilitates palladium-catalyzed cross-coupling reactions, while the ester functionality supports further derivatization. This compound exhibits excellent bench stability and compatibility with standard synthetic workflows in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H317
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Precautionary Statements : P261-P264-P270-P272-P280-P302+P352-P330-P362+P364-P501
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Lot numbers can be found on the outside label of a product: