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CS-W001157 4
Total: USD 88.00

(4-Ethoxyphenyl)methanamine

  • CAS No. 6850-60-8

  • Cat. No. CS-0151466
  • Purity≥96%
  • MDL No.MFCD02225920

*For research and further manufacturing use only, not for direct human use.

(4-Ethoxyphenyl)methanamine|CS-0151466

Structure of 6850-60-8

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General Information

  • CAS No. 6850-60-8
  • Cat. No. CS-0151466
  • Purity ≥96%
  • MDL No. MFCD02225920
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₃NO
  • Molecular Weight 151.21
  • Synonym(s) 4-Ethoxy-benzylamine
  • SMILES CCOC1=CC=C(C=C1)CN

Description

(4-Ethoxyphenyl)methanamine is a bench-stable arylalkyl amine featuring a para-ethoxy substituent that enhances solubility and modulates electronic properties. This compound integrates readily into pharmaceutical intermediates and functional materials, offering predictable reactivity in coupling and derivatization workflows.

Application

(4-Ethoxyphenyl)methanamine serves as a versatile arylalkyl amine building block for medicinal chemistry and materials science. Its ethoxy-substituted phenyl ring enhances solubility and modulates electronic properties, while the primary amine functionality enables straightforward derivatization via amidation, alkylation, or reductive amination. The compound exhibits good bench stability and facilitates efficient purification, making it well-suited for use in standard coupling reactions and heterocycle synthesis.

Synthesis

  • Route1
    • null|null
      89074-22-6
    • ~51%
    • In-stock
      (4-Ethoxyphenyl)methanamine|CS-0151466
      6850-60-8

    References

    • Coxon, Geoffrey D.; Furman, Brian L.; Harvey, Alan L.; McTavish, John; Mooney, Mark H.; Arastoo, Mahmoud; Kennedy, Alan R.; Tettey, Justice M.; Waigh, Roger D. Journal of Medicinal Chemistry, 2009 , vol. 52, # 11 p. 3457 - 3463
  • Route2

    References

    • Yakugaku Zasshi, , vol. 74, p. 889 Chem.Abstr., , p. 2467
  • Route3

    References

    • Journal of the American Chemical Society, , vol. 81, p. 3725,3726

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   35.25
  • LogP   1.544
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   3

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