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CS-W001157 4
Total: USD 88.00

4-Hydroxybenzylamine

  • CAS No. 696-60-6

  • Cat. No. CS-W004078
  • Purity≥96%
  • MDL No.MFCD00870499

*For research and further manufacturing use only, not for direct human use.

4-Hydroxybenzylamine|CS-W004078

Structure of 696-60-6

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General Information

  • CAS No. 696-60-6
  • Cat. No. CS-W004078
  • Purity ≥96%
  • MDL No. MFCD00870499
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₉NO
  • Molecular Weight 123.16
  • Synonym(s) None
  • SMILES OC1=CC=C(CN)C=C1

Description

4-Hydroxybenzylamine features a phenolic hydroxyl group para to a primary amine, enabling dual reactivity in synthetic and biochemical applications. This electron-rich scaffold integrates readily into functionalized molecules, offering enhanced solubility and stability under standard conditions.

Application

4-Hydroxybenzylamine serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and peptide conjugates. Its phenolic hydroxyl and primary amine groups offer orthogonal reactivity for selective derivatization, while the aromatic core ensures metabolic stability. The compound exhibits excellent bench stability and ease of purification, facilitating its use in standard coupling and cyclization protocols.

Synthesis

  • Route1
    • p-Hydroxybenzaldehyde Bisoprolol Impurity|CS-0229513
      123-08-0
    • ~99%
    • In-stock
      4-Hydroxybenzylamine|CS-W004078
      696-60-6

    References

    • Eisai Co., Ltd. Patent: EP1669348 A1, 2006 ; Location in patent: Page/Page column 55 ;
  • Route2
    • 4-Cyanophenol Febuxostat Impurity|CS-0213981
      767-00-0
    • ~97%
    • In-stock
      4-Hydroxybenzylamine|CS-W004078
      696-60-6

    References

    • BRISTOL-MYERS SQUIBB COMPANY Patent: EP696593 A2, 1996 ;
  • Route3

    References

    • Japan Tobacco Inc. Patent: US6017919 A1, 2000 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   46.25
  • LogP   0.8509
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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