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CS-W001157 4
Total: USD 88.00

N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-S-(tert-butyl)-L-cysteine

  • CAS No. 67436-13-9

  • Cat. No. CS-W009724
  • Purity≥97%
  • MDL No.MFCD00037130

*For research and further manufacturing use only, not for direct human use.

N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-S-(tert-butyl)-L-cysteine|CS-W009724

Structure of 67436-13-9

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General Information

  • CAS No. 67436-13-9
  • Cat. No. CS-W009724
  • Purity ≥97%
  • MDL No. MFCD00037130
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₂H₂₅NO₄S
  • Molecular Weight 399.50
  • Synonym(s) None
  • SMILES O=C(O)[C@H](CSC(C)(C)C)NC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O

Description

N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-S-(tert-butyl)-L-cysteine is a protected cysteine derivative featuring a fluorenylmethoxycarbonyl (Fmoc) group for N-terminal protection and a tert-butyl thiol protecting group. This combination enables orthogonal handling in solid-phase peptide synthesis, offering enhanced stability during coupling steps and facilitating selective deprotection under mild conditions.

Synthesis

  • Route1
    • null|null
      28920-43-6
    • In-stock
      S-tert-Butyl-L-cysteine hydrochloride|CS-W014954
      2481-09-6
    • ~80%
    • In-stock
      N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-S-(tert-butyl)-L-cysteine|CS-W009724
      67436-13-9

    References

    • Atherton, Eric; Pinori, Masimo; Sheppard, Robert C. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 2057 - 2064

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   75.63
  • LogP   4.51
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   6

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