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CS-W001157 4
Total: USD 88.00

Boc-Cys(tBu)-OH

  • CAS No. 56976-06-8

  • Cat. No. CS-W022597
  • Purity≥97%
  • MDL No.MFCD00076918

*For research and further manufacturing use only, not for direct human use.

Boc-Cys(tBu)-OH|CS-W022597

Structure of 56976-06-8

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General Information

  • CAS No. 56976-06-8
  • Cat. No. CS-W022597
  • Purity ≥97%
  • MDL No. MFCD00076918
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₂₃NO₄S
  • Molecular Weight 277.38
  • Synonym(s) None
  • SMILES O=C(O)[C@H](CSC(C)(C)C)NC(OC(C)(C)C)=O

Application

Boc-Cys(tBu)-OH serves as a protected cysteine building block for peptide synthesis, offering stable protection of both the amine and thiol functionalities. The Boc group enables efficient N-terminal coupling under standard conditions, while the t-butyl sulfide moiety provides robust protection of the reactive thiol, minimizing oxidation and disulfide scrambling. This stability facilitates straightforward purification and reliable incorporation into complex peptide sequences.

Synthesis

  • Route1
    • null|null
      1070-19-5
    • In-stock
      S-tert-Butyl-L-cysteine hydrochloride|CS-W014954
      2481-09-6
    • ~80%
    • In-stock
      Boc-Cys(tBu)-OH|CS-W022597
      56976-06-8

    References

    • Journal of Organic Chemistry, , vol. 46, # 9 p. 1868 - 1873

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   75.63
  • LogP   2.496
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   4

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