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CS-W001157 4
Total: USD 88.00

m-PEG3-CH2CH2COOH

  • CAS No. 67319-28-2

  • Cat. No. CS-0062370
  • Purity≥97%
  • MDL No.MFCD11041124

*For research and further manufacturing use only, not for direct human use.

m-PEG3-CH2CH2COOH|CS-0062370

Structure of 67319-28-2

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General Information

  • CAS No. 67319-28-2
  • Cat. No. CS-0062370
  • Purity ≥97%
  • MDL No. MFCD11041124
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₂₀O₆
  • Molecular Weight 236.26
  • Synonym(s) None
  • SMILES COCCOCCOCCOCCC(O)=O

Description

m-PEG3-CH2CH2COOH features a mid-chain PEG3 spacer flanked by reactive terminal functionalities: a methylene-linked carboxylic acid for conjugation and an ether-tethered hydrophilic chain. This structure enables stable, water-soluble linkages in bioconjugation workflows, facilitating efficient coupling to amine-bearing biomolecules under mild conditions.

Application

m-PEG3-CH2CH2COOH serves as a versatile bifunctional linker for conjugation and polymer synthesis, combining the solubility and biocompatibility of PEG with a reactive carboxylic acid terminus. It enables efficient amide bond formation under standard coupling conditions, facilitating site-specific attachment to amines in peptides, proteins, or biomolecules. The triethylene glycol spacer provides enhanced flexibility and hydrophilicity, improving solubility and reducing non-specific binding in biological applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   74.22
  • LogP   0.1573
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   12

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