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CS-W001157 4
Total: USD 88.00

Hydroxy-PEG3-acid

  • CAS No. 518044-49-0

  • Cat. No. CS-0109964
  • Purity≥95%
  • MDL No.MFCD26793743

*For research and further manufacturing use only, not for direct human use.

Hydroxy-PEG3-acid|CS-0109964

Structure of 518044-49-0

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General Information

  • CAS No. 518044-49-0
  • Cat. No. CS-0109964
  • Purity ≥95%
  • MDL No. MFCD26793743
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₈O₆
  • Molecular Weight 222.24
  • Synonym(s) None
  • SMILES O=C(O)CCOCCOCCOCCO

Description

Hydroxy-PEG3-acid is a water-soluble, bifunctional linker featuring a terminal carboxylic acid and hydroxyl group separated by a three-ethylene glycol unit. This structure enables conjugation to biomolecules via amine-reactive coupling while maintaining solubility and stability under physiological conditions.

Application

Hydroxy-PEG3-acid serves as a versatile bifunctional linker for conjugation and solubilization in synthetic chemistry. The terminal hydroxyl group enables derivatization via esterification or ether formation, while the carboxylic acid facilitates amide coupling or salt formation. Its three-ethylene glycol unit provides enhanced aqueous solubility and stability, making it ideal for bioconjugation, peptide modification, and the synthesis of functionalized polymers and drug delivery systems.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   85.22
  • LogP   -0.4968
  • H_Acceptors   5
  • H_Donors   2
  • Rotatable_Bonds   11

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