Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

Boc-D-Homoserine lactone

  • CAS No. 67198-86-1

  • Cat. No. CS-W022601
  • Purity≥97%
  • MDL No.MFCD09037376

*For research and further manufacturing use only, not for direct human use.

Boc-D-Homoserine lactone|CS-W022601

Structure of 67198-86-1

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 67198-86-1
  • Cat. No. CS-W022601
  • Purity ≥97%
  • MDL No. MFCD09037376
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₅NO₄
  • Molecular Weight 201.22
  • Synonym(s) (R)-2-Boc-Amino-Γ-Butyrolactone
  • SMILES O=C1OCC[C@H]1NC(OC(C)(C)C)=O

Description

Boc-D-Homoserine lactone features a protected D-homoserine scaffold with a stable carbamate group, enabling reliable incorporation into peptide synthesis. The lactone ring provides structural rigidity and enhanced solubility in organic solvents, facilitating efficient coupling reactions under standard conditions.

Application

Boc-D-Homoserine lactone serves as a stable, bench-ready building block for the synthesis of D-homoserine-containing peptides and bioactive heterocycles. Its protected hydroxyl and amine functionalities enable orthogonal transformations in peptide coupling and cyclization protocols. The lactone ring facilitates regioselective ring-opening reactions, supporting efficient access to chiral intermediates for medicinal chemistry campaigns.

Synthesis

  • Route1

    References

    • Kelley, Brandon T.; Joullie, Madeleine M. Organic Letters, 2010 , vol. 12, # 19 p. 4244 - 4247
  • Route2

    References

    • Martinkova, Miroslava; Gonda, Jozef; Dzoganova, Martina Collection of Czechoslovak Chemical Communications, 2006 , vol. 71, # 8 p. 1199 - 1210
  • Route3
    • null|null
      224192-24-9
    • ~56%
    • In-stock
      Boc-D-Homoserine lactone|CS-W022601
      67198-86-1

    References

    • Shikata, Keiji; Niiro, Hayato; Azuma, Hideki; Tachibana, Taro; Ogino, Kenji Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 4 p. 613 - 616

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   64.63
  • LogP   0.8266
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • Boc-D-Homoserine lactone sigmaBoc-D-Homoserine lactone manufacturerBoc-D-Homoserine lactone priceBoc-D-Homoserine lactone structureBoc-D-Homoserine lactone SDSbuy Boc-D-Homoserine lactoneBoc-D-Homoserine lactone supplierBoc-D-Homoserine lactone usesBoc-D-Homoserine lactone molecular weightprice of Boc-D-Homoserine lactoneBoc-D-Homoserine lactone chemical name formula of Boc-D-Homoserine lactone
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label