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CS-W001157 4
Total: USD 88.00

3-Aminodihydrofuran-2(3H)-one hydrochloride

  • CAS No. 42417-39-0

  • Cat. No. CS-0051531
  • Purity≥97%
  • MDL No.MFCD27977179

*For research and further manufacturing use only, not for direct human use.

3-Aminodihydrofuran-2(3H)-one hydrochloride|CS-0051531

Structure of 42417-39-0

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General Information

  • CAS No. 42417-39-0
  • Cat. No. CS-0051531
  • Purity ≥97%
  • MDL No. MFCD27977179
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₈ClNO₂
  • Molecular Weight 137.56
  • Synonym(s) DL-Homoserine Lactone hydrochloride
  • SMILES Cl.NC1CCOC1=O

Description

3-Aminodihydrofuran-2(3H)-one hydrochloride is a bench-stable, moisture-tolerant heterocyclic amine featuring a reactive carbonyl group and a primary amine. This bifunctional scaffold integrates readily into peptide-like architectures and serves as a key intermediate in the synthesis of bioactive compounds, particularly within medicinal chemistry and natural product derivatization workflows.

Application

3-Aminodihydrofuran-2(3H)-one hydrochloride serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to bioactive scaffolds. Its amine functionality facilitates straightforward derivatization via amidation or alkylation, while the enolizable carbonyl supports nucleophilic addition and condensation reactions. The hydrochloride salt enhances solubility and bench stability, simplifying handling and purification in standard synthetic workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   52.32
  • LogP   -0.3176
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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