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CS-W001157 4
Total: USD 88.00

L-Homoserine lactone hydrochloride

  • CAS No. 2185-03-7

  • Cat. No. CS-W016516
  • Purity≥95%
  • MDL No.MFCD00058172

*For research and further manufacturing use only, not for direct human use.

L-Homoserine lactone hydrochloride|CS-W016516

Structure of 2185-03-7

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General Information

  • CAS No. 2185-03-7
  • Cat. No. CS-W016516
  • Purity ≥95%
  • MDL No. MFCD00058172
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₈ClNO₂
  • Molecular Weight 137.56
  • Synonym(s) None
  • SMILES N[C@@]1([H])CCOC1=O.Cl

Description

L-Homoserine lactone hydrochloride offers a stable, moisture-tolerant platform for synthesizing bioactive heterocycles and peptide mimetics. This bench-stable derivative integrates readily into cascade reactions, enabling efficient access to γ-lactam scaffolds under standard conditions.

Application

L-Homoserine lactone hydrochloride serves as a stable, bench-ready building block for the synthesis of biologically relevant heterocycles and amino acid derivatives. Its well-defined stereochemistry and functional group compatibility facilitate efficient incorporation into peptide mimetics, enzyme inhibitors, and metabolic pathway intermediates. The hydrochloride salt enhances solubility and handling, enabling reliable use in standard coupling and cyclization protocols.

Synthesis

  • Route1

    References

    • US7368600 B2, ; Page/Page column 16-17 ;
  • Route2
    • null|null
      33693-66-2
    • ~86%
    • In-stock
      L-Homoserine lactone hydrochloride|CS-W016516
      2185-03-7

    References

    • Australian Journal of Chemistry, , vol. 38, # 4 p. 621 - 624
  • Route3

    References

    • Tetrahedron Letters, , vol. 50, # 36 p. 5067 - 5070

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   52.32
  • LogP   -0.3176
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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