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CS-W001157 4
Total: USD 88.00

2-Methyl-1H-indole-5-carboxaldehyde

  • CAS No. 671215-52-4

  • Cat. No. CS-0649967
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-Methyl-1H-indole-5-carboxaldehyde|CS-0649967

Structure of 671215-52-4

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General Information

  • CAS No. 671215-52-4
  • Cat. No. CS-0649967
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₉NO
  • Molecular Weight 159.18
  • Synonym(s) None
  • SMILES O=CC1=CC2=C(NC(C)=C2)C=C1

Description

2-Methyl-1H-indole-5-carboxaldehyde features a conjugated aldehyde group at the 5-position of a methyl-substituted indole core, enabling direct integration into heterocyclic scaffolds. The electron-rich indole system enhances reactivity in nucleophilic addition and condensation reactions, while the aldehyde moiety offers a handle for diversification via imine formation or reductive amination. This compound serves as a key intermediate in the synthesis of bioactive molecules and functionalized materials.

Application

2-Methyl-1H-indole-5-carboxaldehyde serves as a versatile building block for heterocyclic synthesis, enabling efficient access to indole-based scaffolds through standard coupling and functionalization reactions. The aldehyde group facilitates nucleophilic additions and condensation processes, while the methyl-substituted indole core offers enhanced stability and compatibility with diverse reaction conditions. Its bench-stable nature and predictable reactivity make it ideal for medicinal chemistry campaigns and process development workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

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Computational Chemistry Data

  • TPSA   32.86
  • LogP   2.28882
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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