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CS-W001157 4
Total: USD 88.00

Indole-5-aldehyde

  • CAS No. 1196-69-6

  • Cat. No. CS-D1053
  • Purity≥98%
  • MDL No.MFCD02093664

*For research and further manufacturing use only, not for direct human use.

Indole-5-aldehyde|CS-D1053

Structure of 1196-69-6

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General Information

  • CAS No. 1196-69-6
  • Cat. No. CS-D1053
  • Purity ≥98%
  • MDL No. MFCD02093664
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₇NO
  • Molecular Weight 145.16
  • Synonym(s) Indole-5-carboxaldehyde
  • SMILES O=CC1=CC=C(NC=C2)C2=C1

Description

Indole-5-carboxaldehyde can be used as a reactant in the:Preparation of curcumin derivatives as anti-proliferative & anti-inflammatory agentsPreparation of analogs of botulinum neurotoxin serotype A protease inhibitorsStereoselective synthesis of dibenzylideneacetone derivatives as -amyloid imaging probesSynthesis of para-para stilbenophanes by McMurry couplingStereoselective synthesis of heteroaromatic (E)-,-unsaturated ketones from aldehydesStructure-based drug design of aurora kinase A inhibitorsPreparation of 5-indolyl linked 15- and 18-membered azacrown ethers to study their cation- interactions.Preparation of bibenzimidazole derivatives substituted 5-indolyl moiety in the study of inhibition of topoisomerase I activity.Synthesis of (5-(4-(3,4,5-trimethoxybenzoyl)-1H-imidazol-2-yl)-1H-indol-2-yl)(3,4,5-trimethoxyphenyl)methanone and radioiodinated indolochalcone.

Synthesis

  • Route1
    • In-stock
      5-Iodo-1H-indole|CS-W004099
      16066-91-4
    • null|null
      201230-82-2
    • ~76%
    • In-stock
      Indole-5-aldehyde|CS-D1053
      1196-69-6

    References

    • Singh, Abhilash S.; Bhanage, Bhalchandra M.; Nagarkar, Jayashree M. Tetrahedron Letters, 2011 , vol. 52, # 18 p. 2383 - 2386
  • Route2

    References

    • Cody, Wayne L.; Holsworth, Daniel D.; Powell, Noel A.; Jalaie, Mehran; Zhang, Erli; Wang, Wei; Samas, Brian; Bryant, John; Ostroski, Robert; Ryan, Michael J.; Edmunds, Jeremy J. Bioorganic and Medicinal Chemistry, 2005 , vol. 13, # 1 p. 59 - 68
  • Route3

    References

    • Journal of Organic Chemistry, , vol. 64, # 6 p. 1823 - 1830

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

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Computational Chemistry Data

  • TPSA   32.86
  • LogP   1.9804
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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