Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

(1H-Indol-5-yl)methanol

  • CAS No. 1075-25-8

  • Cat. No. CS-0091638
  • Purity≥98%
  • MDL No.MFCD02179594

*For research and further manufacturing use only, not for direct human use.

(1H-Indol-5-yl)methanol|CS-0091638

Structure of 1075-25-8

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 1075-25-8
  • Cat. No. CS-0091638
  • Purity ≥98%
  • MDL No. MFCD02179594
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₉NO
  • Molecular Weight 147.17
  • Synonym(s) Indole-5-methanol
  • SMILES OCC1=CC2=C(NC=C2)C=C1

Description

This indole derivative features a hydroxymethyl group at the 5-position, offering enhanced solubility and reactivity in synthetic transformations. The scaffold integrates readily into bioactive molecule frameworks, serving as a key intermediate for pharmaceutical and agrochemical applications under standard conditions.

Application

(1H-Indol-5-yl)methanol serves as a versatile building block in medicinal chemistry, enabling efficient functionalization at the indole C5 position. Its benzylic alcohol functionality facilitates oxidation to the aldehyde or carboxylic acid, and it participates reliably in coupling reactions, including Mitsunobu transformations and Suzuki-Miyaura cross-couplings. The compound exhibits good bench stability and is compatible with standard purification methods, making it a practical reagent for synthesizing substituted indoles and heterocyclic scaffolds relevant to drug discovery.

Synthesis

  • Route1

    References

    • VERNALIS (R and D) LTD; STOKES, Stephen; FOLOPPE, Nicolas; FIUMANA, Andrea; DRYSDALE, Martin; BEDFORD, Simon; WEBB, Paul Patent: WO2011/10083 A1, 2011 ; Location in patent: Page/Page column 20; 27; 28 ; WO 2011/010083 A1
  • Route2

    References

    • Somei, Masanori; Saida, Yoshihiro; Komura, Naoko Chemical and Pharmaceutical Bulletin, 1986 , vol. 34, # 10 p. 4116 - 4125
  • Route3

    References

    • Tlili, Anis; Schranck, Johannes; Neumann, Helfried; Beller, Matthias Chemistry - A European Journal, 2012 , vol. 18, # 50 p. 15935 - 15939

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   36.02
  • LogP   1.6602
  • H_Acceptors   1
  • H_Donors   2
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • (1H-Indol-5-yl)methanol sigma(1H-Indol-5-yl)methanol manufacturer(1H-Indol-5-yl)methanol price(1H-Indol-5-yl)methanol structure(1H-Indol-5-yl)methanol SDSbuy (1H-Indol-5-yl)methanol(1H-Indol-5-yl)methanol supplier(1H-Indol-5-yl)methanol uses(1H-Indol-5-yl)methanol molecular weightprice of (1H-Indol-5-yl)methanol(1H-Indol-5-yl)methanol chemical name formula of (1H-Indol-5-yl)methanol
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label