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Structure of 32996-16-0
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Ethyl 1H-indole-5-carboxylate features a substituted indole core with a carboxylate ester at the C5 position, enabling direct incorporation into diverse heterocyclic syntheses. This bench-stable, moisture-tolerant reagent integrates readily into transition-metal-catalyzed coupling reactions and serves as a key building block for bioactive molecule scaffolds.
Ethyl 1H-indole-5-carboxylate serves as a versatile building block in heterocyclic synthesis, enabling efficient access to indole-based scaffolds through standard functional group transformations. Its ethyl ester group facilitates nucleophilic acyl substitution and reduction reactions, while the indole core offers predictable regioselectivity in electrophilic and transition-metal-catalyzed couplings. Bench-stable and readily purified by chromatography, it functions reliably in medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: