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CS-W001157 4
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(S)-3-(4-(tert-Butoxy)phenyl)-2-((tert-butoxycarbonyl)(methyl)amino)propanoic acid

  • CAS No. 66638-37-7

  • Cat. No. CS-0312091
  • Purity≥98%
  • MDL No.MFCD02684472

*For research and further manufacturing use only, not for direct human use.

(S)-3-(4-(tert-Butoxy)phenyl)-2-((tert-butoxycarbonyl)(methyl)amino)propanoic acid|CS-0312091

Structure of 66638-37-7

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General Information

  • CAS No. 66638-37-7
  • Cat. No. CS-0312091
  • Purity ≥98%
  • MDL No. MFCD02684472
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₉H₂₉NO₅
  • Molecular Weight 351.44
  • Synonym(s) N-α-(t-Butoxycarbonyl)-N-α-methyl-O-(t-butyl)-L-tyrosine
  • SMILES O=C(O)[C@H](CC1=CC=C(C=C1)OC(C)(C)C)N(C(OC(C)(C)C)=O)C

Description

This chiral building block features a (S)-configured backbone with a para-tert-butoxyphenyl group and a tert-butoxycarbonyl-methylamino side chain, enabling direct incorporation into peptide scaffolds. The sterically protected functionality ensures stability during synthesis and purification under standard conditions.

Application

(S)-3-(4-(tert-Butoxy)phenyl)-2-((tert-butoxycarbonyl)(methyl)amino)propanoic acid serves as a versatile chiral building block for medicinal chemistry, enabling efficient access to biologically relevant scaffolds. The protected amine and carboxylic acid functionalities offer orthogonal reactivity, facilitating peptide coupling and selective deprotection sequences. Bench-stable and readily purified by standard chromatography, it functions effectively in multi-step syntheses requiring stereocontrol and functional group compatibility.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362+P364

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Computational Chemistry Data

  • TPSA   76.07
  • LogP   3.7265
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   5

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