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Structure of 5545-54-0
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Z-Tyr(tBu)-OH is a protected tyrosine derivative featuring a benzyloxycarbonyl (Z) group at the N-terminus and a tert-butyl ester at the phenolic oxygen. This configuration enables selective incorporation into peptide chains during solid-phase synthesis, offering enhanced stability and reduced side reactions under standard coupling conditions.
Z-Tyr(tBu)-OH serves as a protected tyrosine building block for peptide synthesis, offering stable handling and orthogonal protection. The benzyloxycarbonyl (Z) group enables selective deprotection under mild hydrogenolysis, while the tert-butyl ester facilitates efficient coupling and subsequent cleavage. This dual protection scheme supports high-yielding amide bond formation in standard solid-phase and solution-phase workflows, making Z-Tyr(tBu)-OH a reliable scaffold for synthesizing bioactive peptides and peptidomimetics.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: