Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

2-Bromoisonicotinic acid

  • CAS No. 66572-56-3

  • Cat. No. CS-W002805
  • Purity≥98%
  • MDL No.MFCD01646069

*For research and further manufacturing use only, not for direct human use.

2-Bromoisonicotinic acid|CS-W002805

Structure of 66572-56-3

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 66572-56-3
  • Cat. No. CS-W002805
  • Purity ≥98%
  • MDL No. MFCD01646069
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₄BrNO₂
  • Molecular Weight 202.01
  • Synonym(s) None
  • SMILES O=C(O)C1=CC=NC(Br)=C1

Description

2-Bromoisonicotinic acid is a bench-stable, moisture-tolerant heterocyclic building block featuring a bromine atom at the 2-position of the pyridine ring. This strategic substitution enables direct coupling in cross-coupling reactions and facilitates downstream functionalization in medicinal chemistry and materials synthesis.

Application

2-Bromoisonicotinic acid serves as a versatile building block in heterocyclic synthesis, enabling direct functionalization at the pyridine ring’s C2 position. Its bromo group facilitates palladium-catalyzed cross-coupling reactions, including Suzuki and Stille couplings, while the carboxylic acid moiety allows for derivatization via amide or ester formation. The compound exhibits good bench stability and is compatible with standard purification methods, making it a practical choice for medicinal chemistry and process development workflows.

Synthesis

  • Route1

    References

    • US2011/111046 A1, ; Page/Page column 17; 18 ;
  • Route2
    • In-stock
      2-Bromo-4-methylpyridine|CS-W007579
      4926-28-7
    • null|null
      1333-82-0
    • ~80%
    • In-stock
      2-Bromoisonicotinic acid|CS-W002805
      66572-56-3

    References

    • US4912101 A1, ;
  • Route3

    References

    • Tetrahedron, , vol. 58, # 22 p. 4429 - 4438

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   50.19
  • LogP   1.5423
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 2-Bromoisonicotinic acid sigma2-Bromoisonicotinic acid manufacturer2-Bromoisonicotinic acid price2-Bromoisonicotinic acid structure2-Bromoisonicotinic acid SDSbuy 2-Bromoisonicotinic acid2-Bromoisonicotinic acid supplier2-Bromoisonicotinic acid uses2-Bromoisonicotinic acid molecular weightprice of 2-Bromoisonicotinic acid2-Bromoisonicotinic acid chemical name formula of 2-Bromoisonicotinic acid
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label