Methyl 2,6-dibromoisonicotinate

Name: Methyl 2,6-dibromoisonicotinate
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 119308-57-5
Cat. No. CS-0049187
Purity≥98%
MDL No.MFCD11042543

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Methyl 2,6-dibromoisonicotinate|CS-0049187

Structure of 119308-57-5

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 119308-57-5
Cat. No. CS-0049187
Purity ≥98%
MDL No. MFCD11042543
Storage 4°C, protect from light, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₅Br₂NO₂
Molecular Weight 294.93
Synonym(s) Methyl 2,6-dibromopyridine-4-carboxylate
SMILES COC(=O)C1=CC(Br)=NC(Br)=C1

Description

Methyl 2,6-dibromoisonicotinate features two bromine atoms at the 2- and 6-positions of the isonicotinate ring, creating a highly electron-deficient pyridine core. This configuration enables direct functionalization in cross-coupling reactions and serves as a key building block for brominated heterocycles in medicinal chemistry and materials science. The methyl ester group provides a handle for further derivatization under standard conditions.

Application

Methyl 2,6-dibromoisonicotinate serves as a versatile building block for the synthesis of brominated heterocycles and functionalized pyridine derivatives. Its dual bromine substituents at the 2- and 6-positions enable selective cross-coupling reactions, facilitating the construction of complex scaffolds in medicinal chemistry and materials science. The methyl ester group provides a handle for further derivatization, while the compound exhibits good bench stability and ease of purification, making it well-suited for routine synthetic workflows.

Synthesis

Route1
- 67-56-1
- In-stock
  
  99-11-6
- ~79%
- In-stock
  
  119308-57-5
References
- Meredith, Erik L.; Beattie, Kimberly; Burgis, Robin; Capparelli, Michael; Chapo, Joseph; Dipietro, Lucian; Gamber, Gabriel; Enyedy, Istvan; Hood, David B.; Hosagrahara, Vinayak; Jewell, Charles; Koch, Keith A.; Lee, Wendy; Lemon, Douglas D.; Mckinsey, Timothy A.; Miranda, Karl; Pagratis, Nikos; Phan, Dillon; Plato, Craig; Rao, Chang; Rozhitskaya, Olga; Soldermann, Nicolas; Springer, Clayton; Van Eis, Maurice; Vega, Richard B.; Yan, Wanlin; Zhu, Qingming; Monovich, Lauren G. Journal of Medicinal Chemistry, 2010 , vol. 53, # 15 p. 5422 - 5438
Route2
- In-stock
  
  99-11-6
- ~%
- In-stock
  
  119308-57-5
References
- US2010/331509 A1, ;

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 39.19
LogP 2.3932
H_Acceptors 3
H_Donors 0
Rotatable_Bonds 1

Other Classifications

Building Blocks Functional Group Ester

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

Methyl 2,6-dibromoisonicotinate sigmaMethyl 2,6-dibromoisonicotinate manufacturerMethyl 2,6-dibromoisonicotinate priceMethyl 2,6-dibromoisonicotinate structureMethyl 2,6-dibromoisonicotinate SDSbuy Methyl 2,6-dibromoisonicotinateMethyl 2,6-dibromoisonicotinate supplierMethyl 2,6-dibromoisonicotinate usesMethyl 2,6-dibromoisonicotinate molecular weightprice of Methyl 2,6-dibromoisonicotinateMethyl 2,6-dibromoisonicotinate chemical name formula of Methyl 2,6-dibromoisonicotinate

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

Methyl 2,6-dibromoisonicotinate

CAS No. 119308-57-5

Recommended Products