Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

Methyl 6-hydroxynicotinate

  • CAS No. 66171-50-4

  • Cat. No. CS-W005768
  • Purity≥95%
  • MDL No.MFCD08436011

*For research and further manufacturing use only, not for direct human use.

Methyl 6-hydroxynicotinate|CS-W005768

Structure of 66171-50-4

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 66171-50-4
  • Cat. No. CS-W005768
  • Purity ≥95%
  • MDL No. MFCD08436011
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₇NO₃
  • Molecular Weight 153.14
  • Synonym(s) Methyl 6-Hydroxy-3-pyridinecarboxylate
  • SMILES O=C(OC)C1=CN=C(O)C=C1

Description

Methyl 6-hydroxynicotinate features a hydroxyl group at the 6-position of the pyridine ring, enabling direct functionalization in synthetic routes. This bench-stable derivative integrates readily into heterocyclic scaffolds and serves as a key intermediate for bioactive compound development.

Application

Methyl 6-hydroxynicotinate serves as a versatile building block in synthetic organic chemistry, enabling efficient access to pyridine-based scaffolds. The ortho-hydroxy and ester functionalities offer complementary reactivity for selective derivatization, including etherification, acylation, and transition-metal-catalyzed coupling reactions. Its bench-stable nature and compatibility with standard purification protocols make it well-suited for medicinal chemistry campaigns and API intermediate synthesis.

Synthesis

  • Route1
    • null|null
      67-56-1
    • 6-Hydroxynicotinic acid Avatrombopag Impurity|CS-0377520
      5006-66-6
    • ~84%
    • In-stock
      Methyl 6-hydroxynicotinate|CS-W005768
      66171-50-4

    References

    • F. HOFFMANN-LA ROCHE AG; DOTT, Pascal; WALDMEIER, Pius Patent: WO2012/52444 A1, 2012 ; Location in patent: Page/Page column 12 ;
  • Route2
    • 6-Hydroxynicotinic acid Avatrombopag Impurity|CS-0377520
      5006-66-6
    • ~%
    • In-stock
      Methyl 6-hydroxynicotinate|CS-W005768
      66171-50-4

    References

    • Monatshefte fuer Chemie, , vol. 22, p. 437
  • Route3
    • 6-Hydroxynicotinic acid Avatrombopag Impurity|CS-0377520
      5006-66-6
    • null|null
      18107-18-1
    • ~97%
    • In-stock
      Methyl 6-hydroxynicotinate|CS-W005768
      66171-50-4

    References

    • Galderma Research and Development Patent: US6534545 B1, 2003 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   59.42
  • LogP   0.5738
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • Methyl 6-hydroxynicotinate sigmaMethyl 6-hydroxynicotinate manufacturerMethyl 6-hydroxynicotinate priceMethyl 6-hydroxynicotinate structureMethyl 6-hydroxynicotinate SDSbuy Methyl 6-hydroxynicotinateMethyl 6-hydroxynicotinate supplierMethyl 6-hydroxynicotinate usesMethyl 6-hydroxynicotinate molecular weightprice of Methyl 6-hydroxynicotinateMethyl 6-hydroxynicotinate chemical name formula of Methyl 6-hydroxynicotinate
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label