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CS-W001157 4
Total: USD 88.00

6-Hydroxynicotinic acid Avatrombopag Impurity

  • CAS No. 5006-66-6

  • Cat. No. CS-0377520
  • Purity≥98%
  • MDL No.MFCD00229359

*For research and further manufacturing use only, not for direct human use.

6-Hydroxynicotinic acid Avatrombopag Impurity|CS-0377520

Structure of 5006-66-6

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General Information

  • CAS No. 5006-66-6
  • Cat. No. CS-0377520
  • Purity ≥98%
  • MDL No. MFCD00229359
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₅NO₃
  • Molecular Weight 139.11
  • Synonym(s) None
  • SMILES OC1=CC=C(C(O)=O)C=N1

Synthesis

  • Route1
    • null|null
      121-44-8
    • ~81%
    • 6-Hydroxynicotinic acid Avatrombopag Impurity|CS-0377520
      5006-66-6

    References

    • Lonza Ltd. Patent: US4609734 A1, 1986 ;
  • Route2

    References

    • Shiao, Min-Jen; Ku, Wei-Shen; Hwu, Jih Ru Heterocycles, 1993 , vol. 36, # 2 p. 323 - 328
  • Route3
    • null|null
      15719-64-9
    • ~%
    • 6-Hydroxynicotinic acid Avatrombopag Impurity|CS-0377520
      5006-66-6

    References

    • Tschitschibabin; Kirssanow Chemische Berichte, 1924 , vol. 57, p. 1164 Zhurnal Russkago Fiziko-Khimicheskago Obshchestva, 1925 , vol. 56, p. 159 Full Text Show Details Tschitschibabin Patent: DE436443 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 15, p. 1486

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   70.42
  • LogP   0.4854
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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