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2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)ethan-1-amine

  • CAS No. 658066-44-5

  • Cat. No. CS-0201438
  • Molecule weight224.61
  • Purity≥95%
  • MDL No.MFCD11848345

*For research and further manufacturing use only, not for direct human use.

2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)ethan-1-amine|CS-0201438

Structure of 658066-44-5

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General Information

  • CAS No. 658066-44-5
  • Cat. No. CS-0201438
  • Purity ≥95%
  • MDL No. MFCD11848345
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₈ClF₃N₂
  • Molecular Weight 224.61
  • Synonym(s) 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)ethanamine
  • SMILES FC(F)(C1=CN=C(CCN)C(Cl)=C1)F

Synthesis

  • Route1

    References

    • Bayer CropScience S.A. Patent: EP1674455 A1, 2006 ; Location in patent: Page/Page column 17 ;
  • Route2
    • Diethyl 2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)malonate|CS-0315111
      172527-71-8
    • ~%
    • In-stock
      2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)ethan-1-amine|CS-0201438
      658066-44-5

    References

    • Fodor, Elena; Maftei, Catalin-Vasile; Mangalagiu, Ionel; Jones, Peter G.; Daniliuc, Constantin-Gabriel; Franz, M. Heiko; Neda, Ion Revue Roumaine de Chimie, 2010 , vol. 55, # 9 p. 559 - 564
  • Route3

    References

    • Fodor, Elena; Maftei, Catalin-Vasile; Mangalagiu, Ionel; Jones, Peter G.; Daniliuc, Constantin-Gabriel; Franz, M. Heiko; Neda, Ion Revue Roumaine de Chimie, 2010 , vol. 55, # 9 p. 559 - 564

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   38.91
  • LogP   2.255
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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