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Structure of 64951-11-7
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Imidazo[1,2-a]pyrimidine-3-carboxylic acid features a rigid heteroaromatic core with a carboxylic acid group at the 3-position, enabling direct conjugation in medicinal chemistry. This scaffold delivers enhanced metabolic stability and favorable solubility profiles, making it a valuable building block for targeted kinase inhibitors and CNS-penetrant drug candidates.
Imidazo[1,2-a]pyrimidine-3-carboxylic acid serves as a versatile scaffold for medicinal chemistry and materials science applications. Its fused heterocyclic core exhibits enhanced metabolic stability and favorable physicochemical properties. The carboxylic acid functionality enables direct derivatization via amide coupling, esterification, or activation for cross-coupling reactions. Bench-stable and readily purified by recrystallization, it functions as a key building block in the synthesis of kinase inhibitors and functionalized aromatic systems.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: