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CS-W001157 4
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(2-(2-Chlorophenyl)thiazol-4-yl)methanol

  • CAS No. 639517-86-5

  • Cat. No. CS-0331508
  • Molecule weight225.69
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(2-(2-Chlorophenyl)thiazol-4-yl)methanol|CS-0331508

Structure of 639517-86-5

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General Information

  • CAS No. 639517-86-5
  • Cat. No. CS-0331508
  • Purity ≥96%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₈ClNOS
  • Molecular Weight 225.69
  • Synonym(s) [2-(2-CHLORO-PHENYL)-THIAZOL-4-YL]-METHANOL
  • SMILES C1=CC=C(C(=C1)C2=NC(=CS2)CO)Cl

Synthesis

  • Route1
    • 2-(2-Chloro-phenyl)-thiazole-4-carboxylic acid ethyl ester|CS-0342173
      132089-36-2
    • ~%
    • 2-(2-Chlorophenyl)thiazole-4-carbaldehyde|CS-0331509
      639517-84-3
    • (2-(2-Chlorophenyl)thiazol-4-yl)methanol|CS-0331508
      639517-86-5

    References

    • PHARMACIA and UPJOHN COMPANY; FINZEL, Barry, C. Patent: WO2004/2977 A1, 2004 ; Location in patent: Page 23-24 ; WO 2004/002977 A1
  • Route2

    References

    • Orr, David; Tolfrey, Alexandra; Percy, Jonathan M.; Frieman, Joanna; Harrison, Zoe A.; Campbell-Crawford, Matthew; Patel, Vipulkumar K. Chemistry - A European Journal, 2013 , vol. 19, # 29 p. 9655 - 9662
  • Route3

    References

    • Mahmoodi, Majid; Aliabadi, Alireza; Emami, Saeed; Safavi, Maliheh; Rajabalian, Saeed; Mohagheghi, Mohammad-Ali; Khoshzaban, Ahad; Samzadeh-Kermani, Alireza; Lamei, Navid; Shafiee, Abbas; Foroumadi, Alireza Archiv der Pharmazie, 2010 , vol. 343, # 7 p. 411 - 416

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H332-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   33.12
  • LogP   2.9558
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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