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CS-W001157 4
Total: USD 88.00

H-Glu-OMe

  • CAS No. 6384-08-3

  • Cat. No. CS-W016141
  • Purity≥95%
  • MDL No.MFCD00171677

*For research and further manufacturing use only, not for direct human use.

H-Glu-OMe|CS-W016141

Structure of 6384-08-3

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General Information

  • CAS No. 6384-08-3
  • Cat. No. CS-W016141
  • Purity ≥95%
  • MDL No. MFCD00171677
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₁NO₄
  • Molecular Weight 161.16
  • Synonym(s) None
  • SMILES O=C(CC[C@@H](C(OC)=O)N)O

Description

H-Glu-OMe features a methyl ester group that enhances solubility and stability in organic solvents, enabling seamless integration into peptide synthesis workflows. This derivative maintains the native glutamic acid side chain functionality while offering improved handling characteristics under standard bench conditions.

Application

H-Glu-OMe serves as a key building block in peptide synthesis, offering a readily accessible precursor for glutamic acid-derived sequences. Its methyl ester functionality enables straightforward coupling reactions and facilitates purification via standard chromatographic methods. The side-chain carboxylate remains protected, ensuring compatibility with orthogonal strategies and enabling selective derivatization in complex peptide architectures.

Synthesis

  • Route1
    • null|null
      1293992-27-4
    • ~%
    • In-stock
      H-Glu-OMe|CS-W016141
      6384-08-3

    References

    • Tetrahedron, , vol. 67, # 13 p. 2422 - 2426
  • Route2
    • Benzyl n-[(3S)-2,6-dioxooxan-3-yl]carbamate|CS-0256477
      4124-76-9
    • ~%
    • In-stock
      H-Glu-OMe|CS-W016141
      6384-08-3

    References

    • Justus Liebigs Annalen der Chemie, , vol. 655, p. 195 - 210
  • Route3

    References

    • Justus Liebigs Annalen der Chemie, , vol. 655, p. 195 - 210

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   89.62
  • LogP   -0.6485
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   4

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