(R)-4-(((Benzyloxy)carbonyl)amino)-5-methoxy-5-oxopentanoic acid

Name: (R)-4-(((Benzyloxy)carbonyl)amino)-5-methoxy-5-oxopentanoic acid
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 26566-11-0
Cat. No. CS-0129470
Purity≥98%
MDL No.MFCD00798654

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

(R)-4-(((Benzyloxy)carbonyl)amino)-5-methoxy-5-oxopentanoic acid|CS-0129470

Structure of 26566-11-0

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 26566-11-0
Cat. No. CS-0129470
Purity ≥98%
MDL No. MFCD00798654
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₄H₁₇NO₆
Molecular Weight 295.29
Synonym(s) z-d-Glu-ome
SMILES O=C(O)CC[C@@H](NC(OCC1=CC=CC=C1)=O)C(OC)=O

Description

(R)-4-(((Benzyloxy)carbonyl)amino)-5-methoxy-5-oxopentanoic acid features a chiral center at the C4 position, enabling stereocontrolled synthesis in peptide and macrocycle workflows. The benzyloxycarbonyl (Cbz) group provides robust N-terminal protection, while the methoxy-ketone functionality offers a handle for selective derivatization under mild conditions. This compound combines stability with orthogonal reactivity, streamlining access to complex scaffolds.

Application

(R)-4-(((Benzyloxy)carbonyl)amino)-5-methoxy-5-oxopentanoic acid serves as a versatile building block for the synthesis of β-amino carbonyl compounds and heterocyclic scaffolds. Its well-defined stereochemistry and orthogonal functionality—combining a benzyl ester, amine, and α-ketoester group—enable selective transformations in peptide-like sequences and complex molecule assembly. Bench-stable and amenable to standard purification methods, it facilitates efficient downstream derivatization in medicinal chemistry and process development workflows.

Synthesis

Route1
- 56877-41-9
- ~%
- In-stock
  
  5672-83-3
- In-stock
  
  26566-11-0
References
- Van Heerbeek, Rieko; Kamer, Paul C. J.; Van Leeuwen, Piet N.M.W.; Reek, Joost N.H. Organic and Biomolecular Chemistry, 2006 , vol. 4, # 2 p. 211 - 223
Route2
- 67-56-1
- 97975-57-0
- ~91%
- In-stock
  
  26566-11-0
References
- Shirude, Pravin S.; Kumar, Vaijayanti A.; Ganesh, Krishna N. Tetrahedron, 2004 , vol. 60, # 42 p. 9485 - 9491
Route3
- In-stock
  
  51644-83-8
- ~%
- In-stock
  
  26566-11-0
References
- Van Heerbeek, Rieko; Kamer, Paul C. J.; Van Leeuwen, Piet N.M.W.; Reek, Joost N.H. Organic and Biomolecular Chemistry, 2006 , vol. 4, # 2 p. 211 - 223

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 101.93
LogP 1.3192
H_Acceptors 5
H_Donors 2
Rotatable_Bonds 7

Other Classifications

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Unnatural Amino Acid Derivatives

Key Words

26566-11-0 sigma26566-11-0 manufacturer26566-11-0 price26566-11-0 structure26566-11-0 SDSbuy 26566-11-026566-11-0 supplier26566-11-0 uses26566-11-0 molecular weightprice of 26566-11-026566-11-0 chemical name formula of 26566-11-0

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

(R)-4-(((Benzyloxy)carbonyl)amino)-5-methoxy-5-oxopentanoic acid

CAS No. 26566-11-0

Recommended Products

General Information

Description

Application

Synthesis

References

References

References

Safety Information

Quality Control

Computational Chemistry Data

Similar Products

Other Classifications

Recently Viewed Products

Key Words