Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

2-(6-Bromopyridin-2-yl)propan-2-ol

  • CAS No. 638218-78-7

  • Cat. No. CS-M1915
  • Purity≥95%
  • MDL No.MFCD16657880

*For research and further manufacturing use only, not for direct human use.

2-(6-Bromopyridin-2-yl)propan-2-ol|CS-M1915

Structure of 638218-78-7

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 638218-78-7
  • Cat. No. CS-M1915
  • Purity ≥95%
  • MDL No. MFCD16657880
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₀BrNO
  • Molecular Weight 216.08
  • Synonym(s) 2-(6-bromopyridine) -2-propanol
  • SMILES BrC1=CC=CC(C(C)(C)O)=N1

Description

This boronate-bearing pyridine derivative features a sterically hindered tertiary alcohol, enabling stable coupling in Suzuki-Miyaura reactions. The 6-bromopyridyl group facilitates selective functionalization, while the bench-stable, moisture-tolerant structure simplifies handling in synthetic workflows.

Application

2-(6-Bromopyridin-2-yl)propan-2-ol serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its stable bromo functionality. The tertiary alcohol group provides steric bulk and enhances metabolic stability, while the pyridine ring offers coordination potential for metal catalysts. Its bench-stable nature and compatibility with standard coupling protocols facilitate efficient synthesis of complex heterocyclic scaffolds.

Synthesis

  • Route1
    • In-stock
      2,6-Dibromopyridine|CS-W008833
      626-05-1
    • null|null
      67-64-1
    • ~98%
    • In-stock
      2-(6-Bromopyridin-2-yl)propan-2-ol|CS-M1915
      638218-78-7

    References

    • ELI LILLY AND COMPANY Patent: WO2009/131814 A2, 2009 ; Location in patent: Page/Page column 40 ; WO 2009/131814 A2
  • Route2
    • In-stock
      2-Acetyl-6-bromopyridine|CS-W002593
      49669-13-8
    • null|null
      75-16-1
    • ~98%
    • In-stock
      2-(6-Bromopyridin-2-yl)propan-2-ol|CS-M1915
      638218-78-7

    References

    • Britton, Thomas Charles; Dehlinger, Veronique; Fivush, Adam Michael; Hollinshead, Sean Patrick; Vokits, Benjamin Paul Patent: US2009/253750 A1, 2009 ; Location in patent: Page/Page column 10 ;
  • Route3
    • null|null
      917-64-6
    • In-stock
      Methyl 6-bromopicolinate|CS-M1028
      26218-75-7
    • ~%
    • In-stock
      2-(6-Bromopyridin-2-yl)propan-2-ol|CS-M1915
      638218-78-7

    References

    • Sagara, Takeshi; Otsuki, Sachie; Sunami, Satoshi; Sakamoto, Toshihiro; Niiyama, Kenji; Yamamoto, Fuyuki; Yoshizumi, Takashi; Furuyama, Hidetomo; Goto, Yasuhiro; Bamba, Makoto; Takahashi, Keiji; Hirai, Hiroshi; Nishibata, Toshihide Patent: US2007/254892 A1, 2007 ; Location in patent: Page/Page column 51 ; US 20070254892 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313-P362+P364

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   33.12
  • LogP   2.0715
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 2-(6-Bromopyridin-2-yl)propan-2-ol sigma2-(6-Bromopyridin-2-yl)propan-2-ol manufacturer2-(6-Bromopyridin-2-yl)propan-2-ol price2-(6-Bromopyridin-2-yl)propan-2-ol structure2-(6-Bromopyridin-2-yl)propan-2-ol SDSbuy 2-(6-Bromopyridin-2-yl)propan-2-ol2-(6-Bromopyridin-2-yl)propan-2-ol supplier2-(6-Bromopyridin-2-yl)propan-2-ol uses2-(6-Bromopyridin-2-yl)propan-2-ol molecular weightprice of 2-(6-Bromopyridin-2-yl)propan-2-ol2-(6-Bromopyridin-2-yl)propan-2-ol chemical name formula of 2-(6-Bromopyridin-2-yl)propan-2-ol
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label