Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

1,3,5-Trichloro-2-iodobenzene

  • CAS No. 6324-50-1

  • Cat. No. CS-0314644
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

1,3,5-Trichloro-2-iodobenzene|CS-0314644

Structure of 6324-50-1

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 6324-50-1
  • Cat. No. CS-0314644
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₂Cl₃I
  • Molecular Weight 307.34
  • Synonym(s) 2-Iodo-1,3,5-trichlorobenzene
  • SMILES C1=C(C=C(C(=C1Cl)I)Cl)Cl

Description

1,3,5-Trichloro-2-iodobenzene features a highly electron-deficient aromatic core stabilized by three chlorine atoms and a reactive iodine substituent. This configuration enables efficient coupling reactions in cross-coupling protocols, particularly in palladium-catalyzed transformations. The compound exhibits excellent bench stability and handles well under standard conditions, making it a reliable reagent for synthesizing complex aryl architectures.

Application

1,3,5-Trichloro-2-iodobenzene serves as a versatile aryl halide building block in palladium-catalyzed cross-coupling reactions. The ortho-iodine enables efficient C–C bond formation via Suzuki, Stille, or Negishi coupling, while the three flanking chlorines provide steric and electronic modulation. Its bench-stable crystalline form facilitates handling and purification, making it well-suited for iterative synthesis of complex aromatic scaffolds in medicinal chemistry and materials science.

Synthesis

  • Route1
    • null|null
      634-93-5
    • ~79%
    • In-stock
      1,3,5-Trichloro-2-iodobenzene|CS-0314644
      6324-50-1

    References

    • SYNGENTA CROP PROTECTION LLC; Stierli, Daniel; Walter, Harald Patent: US2013/72535 A1, 2013 ; Location in patent: Paragraph 0126-0128 ;
  • Route2
    • null|null
      108-70-3
    • ~93%
    • In-stock
      1,3,5-Trichloro-2-iodobenzene|CS-0314644
      6324-50-1

    References

    • Mongin, Florence; Marzi, Elena; Schlosser, Manfred European Journal of Organic Chemistry, 2001 , # 14 p. 2771 - 2777
  • Route3
    • null|null
      401631-89-8
    • ~88%
    • null|null
      108-70-3
    • In-stock
      1,3,5-Trichloro-2-iodobenzene|CS-0314644
      6324-50-1

    References

    • Synthesis, , # 14 p. 2180 - 2190

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   0
  • LogP   4.2514
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1,3,5-Trichloro-2-iodobenzene sigma1,3,5-Trichloro-2-iodobenzene manufacturer1,3,5-Trichloro-2-iodobenzene price1,3,5-Trichloro-2-iodobenzene structure1,3,5-Trichloro-2-iodobenzene SDSbuy 1,3,5-Trichloro-2-iodobenzene1,3,5-Trichloro-2-iodobenzene supplier1,3,5-Trichloro-2-iodobenzene uses1,3,5-Trichloro-2-iodobenzene molecular weightprice of 1,3,5-Trichloro-2-iodobenzene1,3,5-Trichloro-2-iodobenzene chemical name formula of 1,3,5-Trichloro-2-iodobenzene
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label