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CS-W001157 4
Total: USD 88.00

(2-Iodophenyl)boronic acid

  • CAS No. 1008106-86-2

  • Cat. No. CS-0174149
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(2-Iodophenyl)boronic acid|CS-0174149

Structure of 1008106-86-2

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General Information

  • CAS No. 1008106-86-2
  • Cat. No. CS-0174149
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₆BIO₂
  • Molecular Weight 247.83
  • Synonym(s) 2-Iodophenylboronic acid
  • SMILES OB(O)C1=CC=CC=C1I

Application

(2-Iodophenyl)boronic acid serves as a versatile building block in palladium-catalyzed cross-coupling reactions, enabling efficient C–C bond formation with aryl halides and other boronic acids. Its ortho-iodo substituent provides enhanced reactivity in Suzuki-Miyaura coupling protocols while maintaining bench stability and ease of purification. The molecule functions as a key intermediate in the synthesis of biaryl scaffolds found in pharmaceuticals and functional materials.

Synthesis

  • Route1
    • null|null
      7647-01-0
    • In-stock
      1,2-Diiodobenzene|CS-W007538
      615-42-9
    • ~81%
    • In-stock
      (2-Iodophenyl)boronic acid|CS-0174149
      1008106-86-2

    References

    • Al-Zoubi, Raed M.; Marion, Olivier; Hall, Dennis G. Angewandte Chemie - International Edition, 2008 , vol. 47, # 15 p. 2876 - 2879
  • Route2

    References

    • Gernigon, Nicolas; Al-Zoubi, Raed M.; Hall, Dennis G. Journal of Organic Chemistry, 2012 , vol. 77, # 19 p. 8386 - 8400,15 Title/Abstract Full Text Show Details Gernigon, Nicolas; Al-Zoubi, Raed M.; Hall, Dennis G. Journal of Organic Chemistry, 2012 , vol. 77, # 19 p. 8386 - 8400
  • Route3

    References

    • Ren, Yun-Lai; Tian, Xin-Zhe; Dong, Chuanhua; Zhao, Shuang; Wang, Jianji; Yan, Mengjie; Qi, Xiaoguang; Liu, Guihua Catalysis Communications, 2013 , vol. 32, p. 15 - 17

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   40.46
  • LogP   -0.029
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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