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CS-W001157 4
Total: USD 88.00

1-Bromo-4-chlorobutane

  • CAS No. 6940-78-9

  • Cat. No. CS-W017647
  • Purity≥98%
  • MDL No.MFCD00001010

*For research and further manufacturing use only, not for direct human use.

1-Bromo-4-chlorobutane|CS-W017647

Structure of 6940-78-9

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General Information

  • CAS No. 6940-78-9
  • Cat. No. CS-W017647
  • Purity ≥98%
  • MDL No. MFCD00001010
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₈BrCl
  • Molecular Weight 171.46
  • Synonym(s) Tetramethylene chlorobromide; 1-Bromo-4-chlorobutane
  • SMILES ClCCCCBr

Description

1-Bromo-4-chlorobutane features a bromine atom at one terminus and a chlorine atom at the opposite end of a four-carbon chain, enabling dual functionalization in synthetic sequences. This bifunctional alkyl halide facilitates efficient coupling reactions and serves as a key intermediate in the construction of complex molecular architectures through stepwise substitution processes.

Application

1-Bromo-4-chlorobutane serves as a versatile dihalide building block for constructing functionalized aliphatic chains and heterocyclic scaffolds. Its complementary reactivity enables sequential functionalization via nucleophilic substitution, facilitating the synthesis of bioactive intermediates and polymer precursors. The molecule exhibits good bench stability and is amenable to purification by distillation or chromatography, supporting reliable use in standard synthetic workflows.

Synthesis

  • Route1
    • In-stock
      2-(Benzyloxy)acetic acid|CS-W002601
      30379-55-6
    • null|null
      109-70-6
    • ~32%
    • In-stock
      1-Bromo-4-chlorobutane|CS-W017647
      6940-78-9

    References

    • Takeda Pharmaceutical Company Limited Patent: EP2455380 A1, 2012 ; Location in patent: Page/Page column 79 ;
  • Route2

    References

    • Maity, D. K.; Mohan, H.; Chattopadhyay, S.; Mittal, J. P. Journal of Physical Chemistry, 1995 , vol. 99, # 32 p. 12195 - 12203
  • Route3
    • null|null
      109-65-9
    • ~%
    • In-stock
      1-Bromo-4-chlorobutane|CS-W017647
      6940-78-9

    References

    • Journal of the American Chemical Society, , vol. 71, p. 3162

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02,GHS07
Signal Word : Warning
UN#: 1993
Class : 3
Packing Group : Ⅲ
Hazard Statements : H226-H302
Precautionary Statements : P210-P233-P240-P241-P242-P243-P264-P270-P280-P330-P370+P378-P501

Quality Control

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Computational Chemistry Data

  • TPSA   0
  • LogP   2.4003
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   3

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